A Young Patient with Metastatic Prostate Adenocarcinoma: A Case Report and Review of Literature

Abstract

Prostate cancer is extremely rare in men under 40 years old, and current guidelines recommend against screening in this patient population. However, recent data show poorer prognosis in younger men with prostate cancer, especially in those with advanced stage disease. Presented and discussed is the case of a 38-year-old Filipino male diagnosed with prostate adenocarcinoma Gleason 9 (4+5) with bone metastasis presenting with urinary retention, suspicious rectal exam findings, and a markedly elevated PSA. The patient underwent transurethral resection of the prostate and concurrent bilateral orchiectomy. With reports of cases such as this one, biopsy might still be indicated to confirm or rule out cancer in a younger patient with a very high suspicion of prostate cancer based on clinical and laboratory findings. Further studies are needed to identify risk factors for development of prostate cancer in this population to achieve early diagnosis and treatment.